Nurofen For Children Cold, Pain, Fever Strawberry Flavour Nurofen For Children Cold, Pain, Fever Strawberry Flavour

This medicine is suitable for the majority of people but certain people should not use it. Talk to your pharmacist or doctor if you are at all unsure.

 Do not give this medicine to your child if: • they have ever had a reaction (e.g. asthma, runny nose, rash, swelling of the face, tongue, lips or throat) after taking ibuprofen, aspirin or other non steroidal anti- inflammatory (NSAID) medicines • they weigh less than 5kg or are under 3 months of age • they are taking any other anti-inflammatory (NSAID) painkillers, or aspirin with a daily dose above 75 mg • they have (or have had two or more episodes) of a stomach ulcer, perforation or bleeding • they have severe kidney, heart or liver failure • they have inherited problems coping with fructose/fruit sugar (hereditary fructose intolerance). This is because the body can make some fructose from the ingredient maltitol. • they have a history of stomach bleeding or perforation after taking ibuprofen or other NSAIDs. Warnings and precautions Talk to your doctor or pharmacist if: • your child has or has had high blood pressure, heart problems or a stroke because there is a small increased risk of heart problems with ibuprofen • your child has a condition which may put them at risk of heart problems, such as diabetes or high cholesterol • your child has asthma or any allergic disease of the lungs • your child has, or has had liver, kidney, heart or bowel problems • your child is dehydrated as there is a risk of kidney problems • your child has SLE (Systemic Lupus Erythematosus, a condition of the immune system) or any similar disease • your child suffers from chronic inflammatory bowel disease such as Crohn’s disease or ulcerative colitis • Your child has an infection. This medicine may hide signs of an infections such as fever and pain. It is therefore possible that this medicine may delay appropriate treatment of infection, which may lead to an increased risk of complications. This has been observed in pneumonia caused by bacteria and bacterial skin infections related to chickenpox. If you give this medicine to your child while they have an infection and their symptoms of the infection persist or worsen, consult a doctor without delay. • During chicken pox (varicella) it is advisable to avoid use of this medicine. Skin reactions • Serious skin reactions have been reported in association with this medicine. You should stop giving this medicine to your child and seek medical attention immediately, if they develop any skin rash, lesion of the mucous membranes, blisters or other signs of allergy since this can be the first signs of a very serious skin reactions

Other medicines and this medicine Tell your doctor or pharmacist if you or your child are taking, have recently taken or might take any other medicines, especially:  other medicines containing ibuprofen or other NSAIDs, including those you can buy over the counter  low dose aspirin (up to 75 mg a day)  diuretics (to help you pass water)  anticoagulants (blood thinning medicines e.g. warfarin)  medicines for high blood pressure (e.g.captopril, atenolol, losartan)  lithium (for mood disorders)  methotrexate (for psoriasis, arthritis and types of cancer)  zidovudine (for HIV)  corticosteroids (an anti-inflammatory drug)  cardiac glycosides (for heart problems)  ciclosporin or tacrolimus (to prevent organ rejection after transplant)  mifepristone (for termination of pregnancy)  quinolone antibiotics (for infections)  SSRI antidepressant drugs  antiplatelet drugs e.g. dipyridamole, clopidogrel. Seek the advice of your doctor or pharmacist if any of the above apply. If you are not sure what types of medicines your child is taking, show the medicine to the doctor or pharmacist.

Other warnings The following warnings are more likely to concern adults. In any case, consider them carefully before giving or taking this medicine. • medicines such as this medicine may be associated with a small increased risk of heart attack ('myocardial infarction') or stroke. Any risk is more likely with high doses and prolonged treatment. Do not exceed the recommended dose or duration of treatment • if you have heart problems, previous stroke or think that you might be at risk of these conditions (for example if you have high blood pressure, diabetes or high cholesterol or are a smoker) you should discuss your treatment with your doctor or pharmacist • in limited studies, ibuprofen appears in the breast milk in very low concentration and is unlikely to affect the breast-fed infant adversely • if you are elderly talk to your doctor before using this medicine.

Like all medicines, this medicine can cause side effects, although not everybody gets them. The most common side effect is irritation of the stomach which can cause problems such as indigestion and heartburn. If your child experiences any of the following, stop giving this medicine and tell your doctor immediately: • blood in the stools (faeces/motions) • black tarry stools• vomiting blood or dark particles that look like coffee grounds • unexplained wheezing, asthma, shortness of breath, skin rash (which may be severe with blistering or peeling of the skin), itching or bruising, severe skin reactions including Stevens-Johnson syndrome, racing heart, fluid retention (swollen ankles or decreased levels of passing urine) • stiff neck, headache, nausea, vomiting, fever and disorientation. • face, tongue or throat swelling (these can be signs of serious allergic reactions) • A severe skin reaction known as DRESS (Drug reaction with eosinophilia and systemic symptoms) syndrome can occur.

Symptoms of DRESS include: skin rash, fever, swelling of lymph nodes and an increase of eosinophils (a type of white blood cells). • A red, scaly widespread rash with bumps under the skin and blisters mainly localised on the skin folds, trunk, and upper extremities accompanied by fever at the initiation of treatment (acute generalised exanthematous pustulosis) (frequency not known) . If your child experiences any of the following side effects, stop giving this medicine and tell your doctor: • unexplained stomach pain, indigestion, heartburn, nausea or vomiting • yellowing of the eyes, pale stools and dark urine (these can be signs of kidney or liver problems) • severe sore throat with high fever • unexplained bruising or bleeding, tiredness, getting more infections than normal, such as mouth ulcers, colds, sore throat, fever. (These can be signs of anaemia or other blood disorders.)

Other side effects which may occur are: Uncommon: may affect up to 1 in 100 people • headache Rare: may affect up to 1 in 1,000 people • diarrhoea, wind or constipation. Tell your doctor if these last for more than a few days or become troublesome Very rare: may affect up to 1 in 10,000 people • kidney or liver problems may occur with Ibuprofen • stroke or heart problems may occur with Ibuprofen. This is unlikely at the dose level given to children • worsening of colitis and Crohn’s disease • high blood pressure. • stomach ulcer, bleeding of the stomach, inflammation of the stomach lining Not known: frequency cannot be estimated from the available data: • in exceptional cases, serious infections of the skin and soft tissues have occurred during chicken pox (varicella) • skin becomes sensitive to light

 Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.

For oral and short-term use only. Shake the bottle well before use.

• Use the syringe inside to measure the dose accurately. Read the enclosed leaflet carefully before use.
• Not suitable for children under 3 months of age or weighing less than 5kg.

Fever caused by immunisation:

• Babies and children 3 months and over - Weighing more than 5kg: One 2.5ml dose if necessary give second 2.5ml dose 6hrs later
• Do not give more than 2 doses in a 24 hour period. If the fever is not reduced, consult your doctor.

Fever, pain and symptoms of cold and flu:

• 3 - 6 months - Weighing over 5kg: One 2.5ml dose 3 times a day. Do not use for more than 24 hours. If symptoms persist after 24 hours or worsen, consult your doctor.
• 6 - 12 months: One 2.5ml dose 3 or 4 times in 24 hrs
• 1 - 3 years: One 5ml dose 3 times in 24 hrs
• 4 - 6 years: One 7.5ml (5ml 2.5ml) dose 3 times in 24 hrs
• 7 - 9 years: One 10ml (5ml 5ml) dose 3 times in 24 hrs

Doses should be given every 6 - 8 hours. Leave at least 4 hours between doses. Do not take more than the recommended dose in 24 hours. For children above 6 months, if symptoms persist after 3 days or worsen, consult your doctor.

The active ingredient is Ibuprofen 100 mg per 5ml of medicine.

The other ingredients are: Maltitol liquid, water, glycerol, citric acid, sodium citrate, sodium chloride, sodium saccharin, orange or strawberry flavour, xanthan gum, polysorbate 80, domiphen bromide.