Nurofen Express 200mg Liquid Nurofen Express 200mg Liquid

Do not take these capsules if you: • are allergic to ibuprofen or any of the other ingredients of this product (see section 6), or to aspirin or other related painkillers • have (or have had two or more episodes of) a stomach ulcer, perforation or bleeding • have had a worsening of asthma, allergic rash or itchy, runny nose or facial swelling when taking similar medicines • ever had stomach bleeding or a perforation when previously taking NSAIDs • are taking other NSAIDs • are taking more than 75 mg of aspirin a day. If you are on low dose aspirin (up to 75mg daily) speak to your doctor or pharmacist before you take this medicine. • have severe liver or kidney problems • have heart problems, high blood pressure or blood coagulation disorder • have breathing difficulties • are in the last 3 months of pregnancy • are under 12 years old Check with your doctor or pharmacist before taking this medicine if you: • have or have had asthma • have kidney, heart, liver, or bowel problems • have high cholesterol or previously have had a heart attack or stroke • have a history of gastrointestinal disease (such as ulcerative colitis, Crohn’s disease) • have systemic lupus erythematosus (a condition of the immune system causing joint pain, skin changes and other organ disorders) • are a smoker • are in the first 6 months of pregnancy. • have an infection. This medicine may hide signs of infections such as fever and pain. It is therefore possible that this medicine may delay appropriate treatment of infection, which may lead to an increased risk of complications. This has been observed in pneumonia caused by bacteria and bacterial skin infections related to chickenpox. If you take this medicine while you have an infection and your symptoms of the infection persist or worsen, consult a doctor without delay. Skin reactions • Serious skin reactions have been reported in association with this medicine. You should stop taking this medicine and seek medical attention immediately, if you develop any skin rash, lesion of the mucous membranes, blisters or other signs of allergy since this can be the first signs of a very serious skin reaction. See section 4. If symptoms persist or worsen, consult your doctor. Taking other medicines To reduce the risk of side effects, do not take this product with other NSAID containing products (e.g.) aspirin, ibuprofen). If you are on low dose aspirin (up to 75mg daily), speak to your doctor or pharmacist before you take this medicine. This medicine may affect or be affected by some other medicines. For example: • as anti-coagulants (i.e. thin blood/prevent clotting e.g. aspirin/acetylsalicylic acid, warfarin, ticlopidine) • to stimulate your heart (e.g. glycosides) • to reduce high blood pressure (ACE-inhibitors such as captopril, beta-blockers such as atenolol medicines, angiotensin-II receptor antagonists such as losartan) • to help you passing water (diuretics) • for the temporary suppression of your immune system (e.g. methotrexate, ciclosporin, tacrolimus) • for mania or depression (e.g. Lithium or SSRIs) • for pregnancy termination (e.g.mifepristone) • for HIV treatment (e.g. zidovudine) Some other medicines may also affect or be affected by the treatment of this medicine. You should therefore always seek the advice of your doctor or pharmacist before you use this medicine with other medicines. Other warnings • This product belongs to a group of medicines which may impair fertility in women. This is reversible on stopping the medicine. It is unlikely that this product, if used occasionally, will affect your chances of becoming pregnant. However, tell you doctor before taking this medicine if you have problems becoming pregnant. • Anti-inflammatory/pain-killer medicines such as ibuprofen may be associated with a small increased risk of heart attack or stroke, particularly when used at high doses. Do not exceed the recommended dose or duration of treatment. • You should discuss your treatment with your doctor or pharmacist before taking this medicine if you: - have heart problems including heart failure, angina (chest pain), or if you have had a heart attack, bypass surgery, peripheral artery disease (poor circulation in the legs of feet due to narrow or blocked arteries), or any kind of stroke (including ‘mini-stroke’ or transient ischaemic attack “TIA”). - have high blood pressure, diabetes, high cholesterol, have a family history of heart disease or stroke, or if you are a smoker. • There is a risk of kidney problems in dehydrated children and adolescents. Pregnancy and breast-feeding Tell your doctor if you become pregnant whilst taking this product. Do not take the capsules if you are in the last 3 months of pregnancy. Avoid the use of this medicine in the first 6 months of pregnancy, unless the doctor advises otherwise. Speak to your doctor or pharmacist for advice before taking any medicine

Like all medicines, this medicine can cause side effects, although not everybody gets them. If you suffer from any of the following, at any time, during your treatment STOP TAKING the medicine and seek immediate medical help: • pass blood in your faeces (stools/motions) • pass black tarry stools • vomit any blood or dark particles that look like coffee grounds • difficulty in breathing, unexplained wheezing, worsening of existing asthma • other allergic type reactions (e.g. swelling of the face or throat, low blood pressure, fast heart rate) • a severe skin reaction known as DRESS syndrome can occur. Symptoms of DRESS include: skin rash, fever, swelling of lymph nodes and an increase of eosinophils (a type of white blood cells). • A red, scaly widespread rash with bumps under the skin and blisters mainly localised on the skin folds, trunk, and upper extremities accompanied by fever at the initiation of treatment (acute generalised exanthematous pustulosis) (frequency not known). See also section 2. STOP TAKING the medicine and tell your doctor if you experience any of the following side effects, or anything unusual happens: • indigestion or heartburn • abdominal pain (pains in your stomach) or other abnormal stomach symptoms. • a skin rash (which may be severe, such as Stevens-Johnson syndrome), itchy skin or blisters Medicines such as this medicine may be associated with a small increased risk of heart attack (myocardial infarction) or stroke. Please tell your doctor or pharmacist if you experience any of the following side effects, they become worse or if you notice any other effects not listed. • oedema (fluid retention), high blood pressure (hypertension) and heart failure • headache • nausea, diarrhoea, constipation, vomiting and flatulence (wind) • skin peeling • kidney and liver disorders • blood disorders. The first signs can be fever, sore throat, mouth ulcers, ‘flu-like symptoms, severe exhaustion, unexplained bleeding and bruising. • meningitis symptoms such as fever and chills, severe headache, nausea, vomiting and stiff neck (in patients with existing auto-immune disorders such as systemic lupus erythematosus). • worsening of colitis or Crohn’s disease (inflammation of the bowel). • skin becomes sensitive to light (frequency not known) If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet please tell your doctor or pharmacist Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine

For oral administration and short-term use only

Adults, children & adolescents between 12 and 18 years: Swallow 1 or 2 capsules with water, up to three times a day as required. Do not chew capsules. Leave at least 4 hours between doses. Do not take more than 6 capsules in any 24 hours

Do not give to children under 12 years of age

Children and adolescents between 12 and 18 years: If the product is required for more than 3 days, or if symptoms worsen a doctor should be consulted.

Adults: If the product is required for more than 10 days, or if symptoms worsen a doctor should be consulted

Active Ingredients: Each liquid capsule contains: Ibuprofen 200mg

Other ingredients: Includes Potassium, Sorbitol and E124. See leaflet for full details