Headache & Pain Relief Medicines

Don't suffer in silence. Treat minor pain, from headaches to joint pain, with a range of painkillers you can trust. Find tablets, creams and gels, from Nurofen, Voltarol and more. Our experienced team of in-house pharmacists work to source the very best pain relief medications and treatments available for our customers. Check out our pain relief products today!

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  • Co-codamol 8/500mg Co-codamol 8/500mg 32 Tablets

    Co-codamol 8/500 tablets can be used for the short-term relief of acute, moderate pain associated with headache, migraine, neuralgia, toothache, dysmenorrhoea and rheumatic pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    215 reviews In Stock
    £3.99
  • Paracetamol 500mg Paracetamol 500mg 32 Capsules

    Paracetamol Capsule 500mg are used for the relief of mild to moderate pain and feverish conditions. It can also help to relieve headaches, toothache, and symptoms of cold and influenza. Pack of 32 capsules.

    139 reviews In Stock
    £3.29
  • Alka-Seltzer XS Alka-Seltzer XS 20 Tablets

    Relieve mild to moderate pain with Alka-Seltzer XS Effervescent Tablets. Also provide symptomatic relief from joint and muscular aches and pains.

    15 reviews In Stock
    £4.99
  • Anadin Extra Anadin Extra 32 Caplets

    Anadin Extra Caplets contain aspirin, paracetamol and caffeine which all help to provide fast, effective pain relief from headaches, aches and pain.

    69 reviews In Stock
    £4.39
  • Migraine Pain Reliever Tens Machine52% off Migraine Pain Reliever Tens Machine

    If you’re one of the six million people in the UK who experience migraines every year, you’ll know how incredibly debilitating they can be. With over 190,000 migraine attacks every day across the country, the LloydsPharmacy migraine pain reliever TENS machine is here to help.

    0 reviews In Stock
    £3.79£7.95
  • Ibuprofen 400mg Ibuprofen 400mg 24 Tablets

    Ibuprofen 400mg Tablets help to relieve mild to moderate pain including rheumatic and muscular pain, sprains and strains, backache, migraine, headache, toothache, period pains, feverishness and symptoms of colds and flu.

    51 reviews In Stock
    £4.59
  • Snowfire Ointment Stick Snowfire Ointment Stick 18g

    Snowfire Ointment Stick is a solid emollient ointment for dry skin. It can be used by those who are prone to dry skin conditions such as chapped hands & chilblains.

    15 reviews In Stock
    £5.00
  • Ibuprofen Tablets 200mg Ibuprofen Tablets 200mg 24 Tablets

    Ibuprofen Tablets 200mg belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAID), which works to reduce inflammation and pain. This medicine helps to reduce discomfort associated with the symptoms of a cold and the flu.

    40 reviews In Stock
    £2.99
  • Panadol Advance 500mg Panadol Advance 500mg 16 Tablets

    Panadol Advance tablets are familiar, paracetamol based, trusted pain relief tablets that provide fast, effective relief of fever and mild to moderate pain, yet is so gentle on the stomach, it can be taken on an empty stomach.

    36 reviews In Stock
    £2.00
  • Panadol Extra Advance Compack20% off Panadol Extra Advance Compack 14 Tablets

    Panadol Extra Advance Tablets Compack provides extra effective pain relief from headaches, period pain and the aches & pains associated with colds & flu. Contains paracetamol.

    10 reviews In Stock
    £2.40£3.00
  • Calpol Infant Suspension - Sugar & Colour Free Calpol Infant Suspension - Sugar & Colour Free 100ml

    CALPOL ® Infant Suspension is a sugar-free and colour-free, strawberry flavoured oral suspension to relieve the symptoms of fever, colds and flu and other common conditions. For infants 2 months + (weighing over 4kg & not premature). Contains paracetamol. For pain and fever. Always read the label. 100ml.

    6 reviews In Stock
    £3.89
  • Disprin Direct Chewable Aspirin Disprin Direct Chewable Aspirin 16 Tablets

    Disprin Direct Chewable Aspirin provides fast and effective pain relief and helps to relieve pain, reduce fever and inflammation.

    34 reviews In Stock
    £2.25
  • Solpadeine Headache Soluble Solpadeine Headache Soluble 16 Tablets

    Solpadeine® Headache Soluble Tablets are formulated to provide fast effective relief from: Headache, Migraine Also suitable for backache, toothache, period pain and rheumatic pain. Solpadeine Headache Soluble Tablets also relieve the fever, sore throat and aches and pains of colds and flu.

    13 reviews In Stock
    £3.29
  • Calpol Six Plus Sugar Free Suspension Sachets18% off Calpol Six Plus Sugar Free Suspension Sachets 12 Pack

    CALPOL ® Six Plus Suspension Sachets are sugar-free, strawberry flavoured oral suspension for children in handy sachets to relieve the symptoms of fever, colds and flu and other common conditions. For 6+ years only. Contains paracetamol. For pain and fever relief. Always read the label. 12 sachets x 5ml.

    1 review In Stock
    £3.69£4.50
  • 4head Headache Relief Stick 4head Headache Relief Stick 3.6g

    4head Headache Relief Stick is specially designed in a convenient retractable stick dispenser, to be applied directly to the forehead as soon as a headache begins.

    26 reviews In Stock
    £4.99
  • Kool N Soothe Migraine Cooling Pads Kool N Soothe Migraine Cooling Pads 4 Pack

    Kool 'n' Soothe Migraine are soft gel sheets designed to provide immediate cooling relief to the severe discomfort associated with migraine and headaches.

    20 reviews In Stock
    £3.55
  • Calpol Six Plus Suspension Sugar Free Calpol Six Plus Suspension Sugar Free 80ml

    CALPOL Six Plus Suspension is a sugar-free, strawberry flavoured oral suspension for children aged 6 years onwards. Helps your child to feel better and relieve the symptoms of fever, colds and flu and other common conditions. Contains paracetamol. For pain and fever relief. Always read the label. 80ml.

    4 reviews In Stock
    £3.99
  • Hedex Extra Hedex Extra 16 Tablets

    Hedex Extra is formulated to provide relief from a headache including migraines.

    25 reviews In Stock
    £2.55
  • Calprofen Ibuprofen Oral Suspension +3 Months10% off Calprofen Ibuprofen Oral Suspension +3 Months 100ml

    Calprofen Ibuprofen Suspension is a sugar and colour free strawberry flavoured oral suspension for children. It can help your child feel better and relieve the symptoms of fever, colds and flu and other common conditions. For infants 3+ months (weighing over 5kg). Always read the label.

    3 reviews In Stock
    £3.77£4.19
  • Care+ Epsom Salts Care+ Epsom Salts 300g

    Epsom salts can be used for relief of occasional constipation or relief of pain from sprains, bruises and boils.

    23 reviews In Stock
    £3.69
  • Feminax Express for Period Pain Relief Feminax Express for Period Pain Relief 16 Tablets

    Feminax Express Tablets help to deliver fast, effective relief from period pain and cramps when you need an immediate relief.

    11 reviews In Stock
    £4.75
  • Panadol Actifast Compack10% off Panadol Actifast Compack 14 Tablets

    Panadol Actifast is a fast acting formula for effective pain relief containing paracetamol. For the symptoms of headache, rheumatic pain, muscular ache/pain, troothache, period pain, cold & flu symptoms.

    9 reviews In Stock
    £2.70£3.00
  • Calpol Infant Suspension Calpol Infant Suspension 100ml

    CALPOL ® Infant Suspension is a strawberry flavoured oral suspension for children to relieve the symptoms of fever, colds and flu and other common conditions. For infants 2 months + (weighing over 4kg & not premature). Contains paracetamol. For pain and fever. Always read the label. 100ml.

    1 review In Stock
    £3.89
  • Disprin Aspirin Soluble Tablets for Pain Relief Disprin Aspirin Soluble Tablets for Pain Relief 32 Tablets

    Disprin Aspirin Soluble Tablets are designed to relieve pain, and reduce fever and inflammation. They can be used for the relief of mild to moderate pain.

    27 reviews In Stock
    £3.89
  • Anadin Paracetamol Anadin Paracetamol 16 Tablets

    Anadin Paracetamol Tablets are effective for lowering a high temperature and easing away aches and pain associated with the fever. These tablets are gentle on your stomach.

    3 reviews In Stock
    £2.09
  • Anadin Ultra 200mg Anadin Ultra 200mg 16 Liquid Capsules

    Anadin Ultra 200mg Liquid Capsules contain ibuprofen to give up to 8 hours relief from pain. Suitable for back pain, joint or rheumatic pain, muscle ache, headaches & migraine.

    5 reviews In Stock
    £3.29
  • Calpol Six Plus Sugar Free Suspension Calpol Six Plus Sugar Free Suspension 100ml

    CALPOL Six Plus Suspension is a sugar-free, strawberry flavoured oral suspension for children aged 6 years onwards. Contains paracetamol. For pain and fever relief. Always read the label. 100 ml

    1 review In Stock
    £4.59
  • Anadin Original Anadin Original 16 Caplets

    Anadin Original Caplets contain aspirin and caffeine for the relief of mild to moderate pain. Suitable for headaches, migraines, nerve pain, period pains, toothache, sore throat, and aches and pains associated with colds and flu.

    11 reviews In Stock
    £2.79
  • Cura-Heat Back & Shoulder Cura-Heat Back & Shoulder 3 Heat Pads

    Cura-Heat Back & Shoulder in an adhesive, air-activated heat pack to provide targeted relief to minor muscular and joint aches and pains.

    16 reviews In Stock
    £3.59
  • Radian B Ibuprofen 5% Gel Radian B Ibuprofen 5% Gel 30g

    Radian B Ibuprofen 5% Gel is a non-steroidal anti-inflammatory topical gel for the relief of pain and inflammation in conditions such as backache, rheumatic and muscular pain, sprains, strains and sports injuries.

    12 reviews In Stock
    £3.15
  • Childrens Paracetamol Sugar Free Suspension 3 Months+ Children's Paracetamol Sugar Free Suspension 3 Months+ 200ml (Flavours Vary)

    Paracetamol 120mg/5ml Sugar Free Suspension 3months+ contains the same active ingredient as Calpol 3+. Paracetamol suspension can be used to treat mild to moderate pain and helps to reduce fever and relieve the symptoms of cold and flu.

    4 reviews In Stock
    £4.39
  • Algesal Local Analgesic Cream Algesal Local Analgesic Cream 50g

    Algesal Local Analgesic Cream is a local analgesic to relieve the symptoms of various muscular and rheumatic pains.

    53 reviews In Stock
    £3.05
  • SolpaOne 1000mg Effervescent SolpaOne 1000mg Effervescent 12 Tablets

    SolpaOne 1000mg an effervescent, single-dose paracetamol tablet ideal for mild to moderate pain relief and for those who have difficulty swallowing pills.

    0 reviews In Stock
    £4.99
  • Nurofen 342mg for Migraine Nurofen 342mg for Migraine 12 Caplets

    Nurofen Migraine Pain 342mg helps to provide targeted pain relief for the pain of a migraine.

    1 review In Stock
    £3.49
  • Panadol Period Pain Panadol Period Pain 14 Tablets

    Panadol Period Pain helps to provide effective relief from the symptoms of period pain, including backache and headache. Contains paracetamol.

    7 reviews In Stock
    £2.95
  • Nurofen Express 200mg Liquid Nurofen Express 200mg Liquid 10 Liquid Capsules

    Nurofen Pain Relief 200mg Soft Capsules are easily swallowed and quickly relieve pain, Nurofen Soft Capsules work where they're needed - at the site of pain.

    2 reviews In Stock
    £3.45
  • Nurofen For Children Orange Nurofen For Children Orange 100ml

    Nurofen For Children Orange Flavour is formulated especially for children to help reduce a fever as well as aches and pains. Suitable for babies from 3 months and weighing over 5kg.

    2 reviews In Stock
    £4.19
  • Nurofen for Children Liquid Strawberry Flavour Nurofen for Children Liquid Strawberry Flavour 100ml

    Nurofen For Children Strawberry works to reduce fever in just 15 minutes and lasts for up to 8 hours, so your child gets a good night's sleep. Nurofen contains 100mg of the active ingredient Ibuprofen.

    9 reviews In Stock
    £4.19
  • Anadin Extra Anadin Extra 16 Caplets

    Anadin Extra Caplets contain aspirin, paracetamol and caffeine which all help to provide fast, effective pain relief from headaches, aches and pain.

    9 reviews In Stock
    £2.49
  • Deep Heat Maximum Strength Deep Heat Maximum Strength 35g

    Deep Heat Maximum Strength offers powerful and targeted pain relief for relieving rheumatic pain, back pain, sciatica, and fibrositis with the relaxing benefits of heat therapy.

    10 reviews In Stock
    £4.99
  • Alka Seltzer Original Pain Relief Alka Seltzer Original Pain Relief 10 Tablets

    Relieve mild to moderate pain with Alka-Seltzer Original Effervescent Tablets. Also provide symptomatic relief from joint and muscular aches and pains.

    17 reviews In Stock
    £3.25
  • Nurofen Express Ibuprofen 256mg Nurofen Express Ibuprofen 256mg 16 Tablets

    Nurofen Express 265mg Tablets target pain twice as fast as any standard ibuprofen tablets. They provide fast, effective relief from a range of different aches and pains.

    4 reviews In Stock
    £3.89
  • Reliviate 0.5% w/w25% off Reliviate 0.5% w/w 30g

    Reliviate Gel is a gel containing the active ingredient piroxicam. Piroxicam belongs to a group of medicines called topical non-steroidal anti-inflammatory drugs (often shortened to NSAIDs) which are applied to the skin to reduce inflammation (swelling) and pain.

    0 reviews In Stock
    £3.59£4.79
  • Cuprofen Maximum Strength 400mg Cuprofen Maximum Strength 400mg 24 Tablets

    Cuprofen Maximum Strength Tablets help to provide powerful pain relief, so you can get on with your day without discomfort. Contains ibuprofen 400mg.

    16 reviews In Stock
    £3.39
  • Deep Heat Rub Deep Heat Rub 35g

    Deep Heat Heat Rub can be massaged into the affected area to help stimulate circulation, relax and oxygenate tense, painful tissue. Treats painful conditions such as rheumatic pain, sciatica, lumbago or fibrositis by providing soothing warmth. Can be used for the treatment of minor sports injuries, and before and after exercise.

    6 reviews In Stock
    £2.59
  • Beechams Powders for Cold & Flu Beechams Powders for Cold & Flu 10 Sachets

    Tackle the symptoms of cold and flu, with Beechams Powders. Containing Asprin and Caffeine to relieve pain so you can carry on with your day. Beechams - Bossing colds since 1926.

    19 reviews In Stock
    £2.99
  • Nurofen Express Ibuprofen 256mg Nurofen Express Ibuprofen 256mg 16 Caplets

    Nurofen Express 256mg 16 Caplets get straight to the source of the pain, delivering relief twice as fast as standard caplets.

    8 reviews In Stock
    £3.99
  • Anadin Ultra 200mg Anadin Ultra 200mg 8 Liquid Capsules

    Anadin Ultra 200mg Liquid Capsules contain ibuprofen to give up to 8 hours relief from pain. Suitable for back pain, joint or rheumatic pain, muscle ache, headaches & migraine.

    7 reviews In Stock
    £3.15
  • Cura Heat Max Cura Heat Max 2 Patches

    Cura-Heat - MAX are maximum sized heat patches, providing up to 24 hours of targeted pain relief to a large area. The patches are especially well-suited to provide relief from acute back pain.

    3 reviews In Stock
    £4.75

Get your headache relief from Chemist Direct

How do you treat a headache?

Headaches, whether they are general, migraines or tension related, they are one of the most common ailments to affect us in our everyday lives. But when they do hit, all we want to do is lay down and shut our eyes. Unfortunately, as we are busy working people, we cannot afford such a luxury, so instead, we look for headache cures.

Need a sinus headache relief remedy?

We stock an array of headache cures that work almost immediately after taking, from trusted brands such as Nurofen, Solpadeine and Anadin, so that you can simply get on with your day.

Look to Chemist Direct to relieve your headache relief woes

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